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Potentially lethal interaction when used together with nitrate medications such as nitroglycerin, isosorbide mononitrate (Imdur), isosorbide dinitrate (Isordil)

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The pathogenesis of organic ED is related to dysfunction of the endothelium. Endothelial cells can become injured through a variety of mechanisms, most of which cause oxidative stress on the tissues. Many of these causes of oxidative stress are related to lifestyle issues which lead to hypertension, diabetes and dyslipidaemia (figure 1). Endothelial cell dysfunction results in reduction of endothelium-dependent vasorelaxation as well as increased adhesion of leukocytes to the endothelium. Endothelial cell injury then leads to a variety of sequelae, including ED, other types of vasoconstriction, atherosclerosis and thrombus formation.18
Talk to your provider if your erection problems have to do with a fear of heart problems. Sexual intercourse is usually safe for men with heart problems. .

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Psychogenic ED was thought to be the most common cause of ED, however, psychologic causes often coexist with physical or functional causes of ED.
Psychoteraphy is often the first form of treatment recommended for depression. Psychotherapy helps depression by helping people understand the behaviors, emotions and ideas that contribute to their depression, regain a sense of control and pleasure in life, and learn coping techniques as well as problem solving skills.

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Unfortunately, some men may not recover their ability to have a natural erection.
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PDE 5 inhibitors are broken down primarily by enzyme, cytochrome P450enzyme CYP3A4. Medications that decrease or increase the activity of CYP3A4 may affect levels and effectiveness of PDE 5 inhibitors. Such drugs include medications for the treatment of HIV (protease inhibitors) and the antifungal medications ketoconazole and itraconazole. Thus caution is recommended.

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With this self-test you can easily find out if there are any serious indications of pathological erectile dysfunction in your body. This test is based on the so-called IIEF-score. IIEF stands for «International Index of Erectile Function». In medicine, the IIEF-score is not only used for the diagnosis of erectile dysfunction, but also for success monitoring of therapies.

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    Social ideas of how men and women are supposed to interact can also contribute to ED. These can include unrealistic expectations about love and sexuality, and inappropriate male and female role models.

    In response, a number of erectile dysfunction treatments have been developed, with varying efficacy and side effects.
    In prescribing sildenafil, a doctor considers the age, general health status, and other medication(s) the patient is taking. The usual starting dose for most men is 50 mg, however, the doctor may increase or decrease the dose depending on side effects and effectiveness. The maximum recommended dose is 100 mg every 24 hours. However, many men will need 100 mg of sildenafil for optimal effectiveness, and some doctors are recommending 100 mg as the starting dose.

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    To do these erectile dysfunction exercises, a man can contract the muscles used to stop urinating. These should be contracted for ten seconds, then relaxed for ten seconds. This can be repeated as many times as possible. After these Kegel exercises are performed, many doctors also recommend that they are repeated, but for one second at a time instead of ten. Any man at any age can suffer from erectile dysfunction.

    A vacuum device is exactly what it sounds like: a tube that brings blood into the penis. You keep the erection by using a penis ring at the base of the penis.
    To learn more about erections, such as what they are and how they form, see Cancer, Sex, and the Male Body.

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    ED can be stressful for men and their partners, and depression can develop from relationship conflict. The man with ED might worry that he is not meeting his partner’s needs and feel that he is inadequate or less masculine. His partner might worry about being attractive enough or suspect that the man is having an affair. If these feelings aren’t brought out into the open, the situation can worsen, with both partners withdrawing, avoiding each other, or missing the intimacy that they once shared.

    There are times when exercises do not create a more significant impact on erectile dysfunction. At these times, it is advised for a man to go for medical treatments. Medication is a very easy and painless way to treat ED issues without any complications. You can always rely on ED medicines when no other thing works on erection failures.
    Several studies support the conclusion that following a Mediterranean-style diet can decrease the risk of E.D. The link between diet and improved erectile function was stronger in men under the age of 60, but it was found in all age groups (Bauer et al., 2020).

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    Various studies have shown that around 11 percent of men experience mild symptoms of ED in their early 30s. And by doing proper exercises and yogas, one can overcome those symptoms to get over their problem before touching their 40s.

    Injection therapy: The modern age of such drug therapies began in 1993 when the injection of papaverine (Pavabid), an alpha-blocker that produces vasodilatation (widening of the blood vessels), was shown to produce erections when injected directly into the penis. Soon afterward, other vasodilators, such as prostaglandin E1 (PGE 1) monotherapy (Caverject, Edex), PGE1 and phentolamine (Regitine), and Trimix (papaverine, phentolamine and prostaglandin E1), were demonstrated to be effective. The benefit of combination therapy is the decreased dosing of each with less side effects. Most important is the reduction of the prostaglandin PGE1 dosing, which is associated to the localized pain.
    Traditional treatments for both problems revolve around lifestyle changes and drugs, Mr Myers and his colleagues said.

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In the process, tubular tubes or Vacuum devices are placed over the penis. As air is tapped out of the cylinder, and the pressure build-up helps to draw blood into the penis. This helps the penis to enlarge A rubber ring is then set around the bottom of the penis to maintain the erection.

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There are a variety of methods for treating erectile dysfunction. Your doctor can discuss all of these options with you in more detail. All decisions regarding your best option for treating E.D. should be made between you and your physician, with consideration given to your individual needs and the pros and cons of each treatment options.

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ED can cause strain on a couple. Many times, men won't get into sexual situations because they are embarrassed. In turn, their partner may feel rejected or inadequate. It's important to talk openly with your partner. Some couples may get treatment for ED together. Other men prefer to get treatment without their partner's knowledge. Not talking about it is the main barrier to getting treatment. The loss of erectile function can have a profound effect on a man. The good news is that ED can often be treated safely and effectively.

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There are several different types of injection therapy ranging from injection of a single chemical (monotherapy) to a combination of chemicals, Bimix and Trimix. The selection of which therapy to use will vary with the severity of your erectile dysfunction and whether or not you tried and had pain with MUSE.

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